Calcium is an essential element of the tissue; the blood contains approximately 10 milligrams per 100 milliliters, about 7 milligrams being in ionized from and about 3 milligrams in colloidal from combined with serum proteins. Usually, animals run deficiency of calcium due to unbalanced feed or the average daily requirement increases during periods of growth, pregnancy and lactation. The symptoms of calcium deficiency appear in the shape of Milk Fever and Hypocalcaemia conditions which can effectively be cured with Milfone. The administration of Calcium is also recommended for the prevention of acute necrosis of the liver arising from poisoning .Calcium Borogluconate (Milfone) is less irritant but highly stable.