TYLOSIN: It is a macrolide antibiotic and has a bacteriostatical activity against mainty gram-positive bacteria and cocci, gram-negative meningococci and gonococci. After oral administration, theraputica blood levels will be achieved within 2-4 hours. DOXYCYCLINE: It belong to a group of the TetracycIine’s and has a bacteriostatic activity against many gram-positive and gram-negative bacteria like Staphylococcus spp. COLISTIN: Colistin a cyclic polypeptide antibiotic has a bactericidal action against selected gram-negative bacteria, The primary bacterial effect of Colistin is a blockade of the cell divition of bacteria followed by a secondary progressive lyses. INDICATION: Infections caused by Tylosin, Doxycycline and Colistin sensitive micro-organisims in calves and poultry especially for gastrointestinal and Mycoplasmal infections. In Poultry mainly of the respiratory tract lnfection. lt is often used during bronchopneumonia in cattle and chronic coughing in horses.