This report presents an overview of HPAI disease events (in poultry and non-poultry including wild birds) reported to the OIE’s early warning system (immediate notification and follow-up reports) by its Members, as well as non-Member Countries, during the period 25 December – 14 January, 2021 through the World Animal Health Information System (WAHIS). The stable situations reported in the six-monthly reports by two countries, namely Egypt and Indonesia, are not described in this report as this data for the second semester 2019 and first and secod semester 2020 will be collected throughout the first semester of 202